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| Reporting Date | Major Shareholder Name | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| 05/13/2024 | FMR LLC | 6.60 M | $284.21 M | 16.72% | 9.87% |
| 05/15/2024 | AVORO CAPITAL ADVISORS LLC | 5.67 M | $243.95 M | 0.00% | 8.47% |
| 05/15/2024 | DRIEHAUS CAPITAL MANAGEMENT LLC | 4.32 M | $186.05 M | -0.54% | 6.46% |
| 05/15/2024 | WELLINGTON MANAGEMENT GROUP LLP | 3.92 M | $168.84 M | -5.78% | 5.86% |
| 05/14/2024 | CAPITAL WORLD INVESTORS | 2.68 M | $115.44 M | 0.00% | 4.01% |
| 05/15/2024 | POLAR CAPITAL HOLDINGS PLC | 2.61 M | $112.45 M | -14.82% | 3.91% |
| 05/15/2024 | PARADIGM BIOCAPITAL ADVISORS LP | 2.48 M | $106.97 M | 16.80% | 3.71% |
| 05/14/2024 | CAPITAL INTERNATIONAL INVESTORS | 2.48 M | $106.59 M | 0.82% | 3.70% |
| 05/15/2024 | COMMODORE CAPITAL LP | 2.17 M | $93.32 M | 0.00% | 3.24% |
| 05/10/2024 | BLACKROCK INC. | 2.12 M | $91.35 M | 2.65% | 3.17% |
| 05/15/2024 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.67 M | $71.98 M | 59.42% | 2.50% |
| 05/14/2024 | PICTET ASSET MANAGEMENT HOLDING SA | 1.52 M | $65.24 M | -25.73% | 2.27% |
| 05/14/2024 | ALLIANCEBERNSTEIN L.P. | 1.47 M | $63.22 M | -6.74% | 2.20% |
| 05/15/2024 | MARSHALL WACE, LLP | 1.45 M | $62.44 M | -5.12% | 2.17% |
| 05/15/2024 | T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | 1.43 M | $61.40 M | 60.06% | 2.13% |
| 05/15/2024 | FIRST LIGHT ASSET MANAGEMENT, LLC | 1.32 M | $56.83 M | -19.77% | 1.97% |
| 05/15/2024 | BRAIDWELL LP | 1.31 M | $56.31 M | -20.60% | 1.96% |
| 05/15/2024 | CITADEL ADVISORS LLC | 1.29 M | $55.41 M | 1.60% | 1.92% |
| 05/15/2024 | ROCK SPRINGS CAPITAL MANAGEMENT LP | 1.26 M | $54.05 M | 0.00% | 1.88% |
| 05/14/2024 | INVESCO LTD. | 1.05 M | $45.18 M | 45.82% | 1.57% |
| 05/15/2024 | BAKER BROS. ADVISORS LP | 993,679 | $42.78 M | 0.00% | 1.49% |
| 05/15/2024 | JANUS HENDERSON GROUP PLC | 941,569 | $40.55 M | -2.54% | 1.41% |
| 05/09/2024 | LORD, ABBETT & CO. LLC | 895,196 | $38.54 M | 24.68% | 1.34% |
| 05/15/2024 | PERCEPTIVE ADVISORS LLC | 892,208 | $38.41 M | -18.95% | 1.33% |
| 05/14/2024 | AFFINITY ASSET ADVISORS, LLC | 837,387 | $36.05 M | 82.04% | 1.25% |
| 05/07/2024 | TIMESSQUARE CAPITAL MANAGEMENT, LLC | 737,173 | $31.74 M | -7.15% | 1.10% |
| 05/14/2024 | FEDERATED HERMES, INC. | 734,900 | $31.64 M | 112.03% | 1.10% |
| 05/15/2024 | AVIDITY PARTNERS MANAGEMENT LP | 710,000 | $30.57 M | -12.99% | 1.06% |
| 05/14/2024 | LOOMIS SAYLES & CO L P | 686,510 | $29.55 M | -3.08% | 1.03% |
| 05/06/2024 | FIRST TURN MANAGEMENT, LLC | 680,389 | $29.29 M | 0.00% | 1.02% |
| 05/15/2024 | BOXER CAPITAL, LLC | 600,000 | $25.83 M | 0.00% | 0.90% |
| 05/01/2024 | FIERA CAPITAL CORP | 576,542 | $24.82 M | 4.25% | 0.86% |
| 05/02/2024 | JENNISON ASSOCIATES LLC | 563,952 | $24.28 M | -0.43% | 0.84% |
| 05/06/2024 | CANDRIAM S.C.A. | 560,884 | $24.15 M | 5.65% | 0.84% |
| 05/15/2024 | ORBIMED ADVISORS LLC | 550,000 | $23.68 M | 0.00% | 0.82% |
| 05/13/2024 | FRANKLIN RESOURCES INC | 542,289 | $23.35 M | 84.56% | 0.81% |
| 05/15/2024 | GREAT POINT PARTNERS LLC | 456,148 | $19.64 M | -23.98% | 0.68% |
| 05/08/2024 | BNP PARIBAS ASSET MANAGEMENT HOLDING S.A. | 416,736 | $17.94 M | 100.00% | 0.62% |
| 05/10/2024 | DIMENSIONAL FUND ADVISORS LP | 410,207 | $17.66 M | 1.87% | 0.61% |
| 05/14/2024 | VESTAL POINT CAPITAL, LP | 400,000 | $17.22 M | 128.57% | 0.60% |
| 05/15/2024 | SAMLYN CAPITAL, LLC | 396,196 | $17.06 M | -5.93% | 0.59% |
| 05/15/2024 | MORGAN STANLEY | 386,199 | $16.63 M | 71.53% | 0.58% |
| 05/15/2024 | ALTIUM CAPITAL MANAGEMENT LP | 348,000 | $14.98 M | 19.78% | 0.52% |
| 05/10/2024 | WESTFIELD CAPITAL MANAGEMENT CO LP | 347,351 | $14.95 M | 46.26% | 0.52% |
| 05/10/2024 | VANGUARD GROUP INC | 335,635 | $14.45 M | 3.75% | 0.50% |
| 05/15/2024 | ALLY BRIDGE GROUP (NY) LLC | 309,369 | $13.32 M | 27.86% | 0.46% |
| 05/15/2024 | GOLDMAN SACHS GROUP INC | 299,774 | $12.91 M | -20.34% | 0.45% |
| 05/15/2024 | BOONE CAPITAL MANAGEMENT LLC | 291,403 | $12.54 M | 14.08% | 0.44% |
| 05/15/2024 | POINT72 ASSET MANAGEMENT, L.P. | 275,859 | $11.88 M | -68.48% | 0.41% |
| 05/15/2024 | TWO SIGMA INVESTMENTS, LP | 274,626 | $11.82 M | -19.23% | 0.41% |
A. During the previous two years, 262 institutional investors and hedge funds held shares of Xenon Pharmaceuticals Inc.. The most heavily invested institutionals were:
FMR LLC: 6.6 M
Avoro Capital Advisors LLC: 5.67 M
DRIEHAUS CAPITAL MANAGEMENT LLC: 4.32 M
WELLINGTON MANAGEMENT GROUP LLP: 3.92 M
Capital World Investors: 2.68 M
Polar Capital Holdings Plc: 2.61 M
A. 109.77% of Xenon Pharmaceuticals Inc. stock is owned by institutional investors.
A. Institutional investors have bought a total of 84.66 M shares in the last 24 months. This purchase volume represents approximately $3.17 B in transactions.
