Recent Quarter Total Invested
$560.94 M
Recent Quarter Institutional Ownership Percentage
42.02%
Total Invested of Last Quarter
$1.18 B
Ownership Percentage of Last Quarter
111.19%
Spyre Therapeutics, Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| FMR LLC | 11/13/2024 | 7.62 M | $224.22 M | 1.54% | 16.82% |
| FAIRMOUNT FUNDS MANAGEMENT LLC | 11/14/2024 | 4.02 M | $118.17 M | 0.00% | 8.87% |
| RTW INVESTMENTS, LP | 11/14/2024 | 3.26 M | $95.83 M | 0.00% | 7.19% |
| PERCEPTIVE ADVISORS LLC | 11/14/2024 | 2.87 M | $84.48 M | -5.23% | 6.34% |
| VR ADVISER, LLC | 11/14/2024 | 2.69 M | $78.98 M | 0.00% | 5.93% |
| BLACKROCK FUNDING, INC. /DE | 11/13/2024 | 2.66 M | $78.32 M | 100.00% | 5.88% |
| VANGUARD GROUP INC | 11/13/2024 | 2.52 M | $73.99 M | 31.62% | 5.55% |
| BRAIDWELL LP | 11/14/2024 | 2.19 M | $64.40 M | -12.91% | 4.83% |
| COMMODORE CAPITAL LP | 11/14/2024 | 1.99 M | $58.47 M | 0.00% | 4.39% |
| PARADIGM BIOCAPITAL ADVISORS LP | 11/14/2024 | 1.27 M | $37.28 M | 100.00% | 2.80% |
| ASSENAGON ASSET MANAGEMENT S.A. | 10/23/2024 | 1.14 M | $33.61 M | 100.00% | 2.52% |
| JANUS HENDERSON GROUP PLC | 11/14/2024 | 1.12 M | $32.92 M | 66.28% | 2.47% |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 11/14/2024 | 1.06 M | $31.03 M | -8.45% | 2.33% |
| DEEP TRACK CAPITAL, LP | 11/14/2024 | 1.00 M | $29.41 M | -43.07% | 2.21% |
| PICTET ASSET MANAGEMENT HOLDING SA | 11/12/2024 | 825,706 | $24.28 M | 113.57% | 1.82% |
| FRANKLIN RESOURCES INC | 11/12/2024 | 760,666 | $23.32 M | 2.53% | 1.68% |
| BOXER CAPITAL, LLC | 11/14/2024 | 696,480 | $20.48 M | 0.00% | 1.54% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 11/14/2024 | 687,080 | $20.21 M | 0.00% | 1.52% |
| AVORO CAPITAL ADVISORS LLC | 11/14/2024 | 598,600 | $17.60 M | -67.45% | 1.32% |
| POLAR CAPITAL HOLDINGS PLC | 11/14/2024 | 500,000 | $14.71 M | 0.00% | 1.10% |
| AFFINITY ASSET ADVISORS, LLC | 11/13/2024 | 498,420 | $14.66 M | -2.92% | 1.10% |
| JEFFERIES FINANCIAL GROUP INC. | 11/14/2024 | 454,807 | $13.38 M | 366.12% | 1.00% |
| NORTHERN TRUST CORP | 11/13/2024 | 314,290 | $9.24 M | 267.21% | 0.69% |
| IKARIAN CAPITAL, LLC | 11/14/2024 | 302,247 | $8.89 M | 100.00% | 0.67% |
| BLACKSTONE INC. | 11/14/2024 | 292,995 | $8.62 M | 0.00% | 0.65% |
| EMERALD ADVISERS, LLC | 10/29/2024 | 292,569 | $8.60 M | 100.00% | 0.65% |
| WOODLINE PARTNERS LP | 11/14/2024 | 264,256 | $7.77 M | 0.62% | 0.58% |
| EMERALD MUTUAL FUND ADVISERS TRUST | 10/29/2024 | 253,550 | $7.46 M | 100.00% | 0.56% |
| WALLEYE CAPITAL LLC | 11/14/2024 | 243,372 | $7.16 M | 61.37% | 0.54% |
| BALYASNY ASSET MANAGEMENT L.P. | 11/14/2024 | 227,950 | $6.70 M | -16.39% | 0.50% |
| LOGOS GLOBAL MANAGEMENT LP | 11/14/2024 | 200,000 | $5.88 M | -65.22% | 0.44% |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 11/14/2024 | 156,481 | $4.60 M | -43.14% | 0.35% |
| SOROS FUND MANAGEMENT LLC | 11/14/2024 | 145,000 | $4.26 M | 0.00% | 0.32% |
| ARMISTICE CAPITAL, LLC | 11/14/2024 | 136,000 | $4.00 M | 0.00% | 0.30% |
| HIGHVISTA STRATEGIES LLC | 11/14/2024 | 105,351 | $3.10 M | -7.22% | 0.23% |
| CANDRIAM S.C.A. | 11/13/2024 | 105,000 | $3.09 M | 0.00% | 0.23% |
| BANK OF NEW YORK MELLON CORP | 11/12/2024 | 104,806 | $3.08 M | -10.94% | 0.23% |
| BOOTHBAY FUND MANAGEMENT, LLC | 11/14/2024 | 91,775 | $2.70 M | 100.00% | 0.20% |
| ENSIGN PEAK ADVISORS, INC | 11/14/2024 | 82,475 | $2.43 M | 0.00% | 0.18% |
| RAFFERTY ASSET MANAGEMENT, LLC | 11/13/2024 | 70,586 | $2.08 M | 5.18% | 0.16% |
| CINCTIVE CAPITAL MANAGEMENT LP | 11/14/2024 | 61,256 | $1.80 M | 100.00% | 0.14% |
| GHOST TREE CAPITAL, LLC | 11/14/2024 | 60,000 | $1.76 M | -76.02% | 0.13% |
| UBS GROUP AG | 11/14/2024 | 57,838 | $1.70 M | 29.96% | 0.13% |
| RHUMBLINE ADVISERS | 11/12/2024 | 53,935 | $1.59 M | 3.93% | 0.12% |
| TD ASSET MANAGEMENT INC | 11/01/2024 | 52,768 | $1.50 M | 50.05% | 0.12% |
| EFG ASSET MANAGEMENT (NORTH AMERICA) CORP. | 11/12/2024 | 52,210 | $1.53 M | 41.95% | 0.12% |
| SWISS NATIONAL BANK | 11/07/2024 | 49,600 | $1.46 M | 37.40% | 0.11% |
| SCHONFELD STRATEGIC ADVISORS LLC | 11/14/2024 | 46,072 | $1.35 M | -41.31% | 0.10% |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 11/13/2024 | 43,460 | $1.28 M | 15.03% | 0.10% |
| SUPERSTRING CAPITAL MANAGEMENT LP | 11/14/2024 | 37,287 | $1.10 M | -18.18% | 0.08% |
Spyre Therapeutics, Inc.institutional Ownership - Frequently Asked Questions
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Who are the largest shareholders of SYRE shares?
During the previous two years, 106 institutional investors and hedge funds held shares of Spyre Therapeutics, Inc.. The most heavily invested institutionals were:
FMR LLC: 7.62 M
Fairmount Funds Management LLC: 4.02 M
RTW INVESTMENTS, LP: 3.26 M
PERCEPTIVE ADVISORS LLC: 2.87 M
VR Adviser, LLC: 2.69 M
BlackRock Funding, Inc. /DE: 2.66 M
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What percentage of Spyre Therapeutics, Inc. stock is owned by institutional investors?
42.02% of Spyre Therapeutics, Inc. stock is owned by institutional investors.
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How much institutional buying is happening at SYRE ?
Institutional investors have bought a total of 44.52 M shares in the last 24 months. This purchase volume represents approximately $1.28 B in transactions.