Milestone Pharmaceuticals Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 11/14/2025 | 6.98 M | $13.95 M | 100.00% | 10.51% |
| PROPEL BIO MANAGEMENT, LLC | 11/12/2025 | 5.12 M | $10.25 M | 186.06% | 7.72% |
| ORBIMED ADVISORS LLC | 11/14/2025 | 3.22 M | $6.44 M | 100.00% | 4.85% |
| MORGAN STANLEY | 11/14/2025 | 2.97 M | $5.94 M | 261.90% | 4.47% |
| SIMPLIFY ASSET MANAGEMENT INC. | 10/20/2025 | 2.83 M | $5.67 M | 186.16% | 4.27% |
| RTW INVESTMENTS, LP | 11/14/2025 | 2.51 M | $5.01 M | 0.00% | 3.78% |
| PATHSTONE HOLDINGS, LLC | 11/13/2025 | 1.00 M | $2.00 M | 100.00% | 1.51% |
| SPHERA FUNDS MANAGEMENT LTD. | 11/14/2025 | 820.00 K | $1.64 M | 100.00% | 1.24% |
| TORONTO DOMINION BANK | 11/14/2025 | 750.00 K | $1.50 M | 0.00% | 1.13% |
| AFFINITY ASSET ADVISORS, LLC | 11/13/2025 | 666.67 K | $1.33 M | 100.00% | 1.00% |
| BOXER CAPITAL MANAGEMENT, LLC | 11/14/2025 | 666.67 K | $1.33 M | 100.00% | 1.00% |
| TWO SIGMA INVESTMENTS, LP | 11/14/2025 | 666.55 K | $1.33 M | 100.00% | 1.00% |
| LION POINT CAPITAL, LP | 11/14/2025 | 658.55 K | $1.32 M | 20.00% | 0.99% |
| CITADEL ADVISORS LLC | 11/14/2025 | 512.07 K | $1.02 M | 100.00% | 0.77% |
| MARSHALL WACE, LLP | 11/13/2025 | 425.03 K | $850.06 K | 100.00% | 0.64% |
| JANE STREET GROUP, LLC | 11/14/2025 | 408.49 K | $816.98 K | 1,179.22% | 0.62% |
| MILLENNIUM MANAGEMENT LLC | 11/14/2025 | 401.56 K | $803.12 K | 100.00% | 0.60% |
| UBS GROUP AG | 11/13/2025 | 397.53 K | $795.07 K | 23.21% | 0.60% |
| GOLDMAN SACHS GROUP INC | 11/14/2025 | 356.57 K | $713.13 K | 198.51% | 0.54% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 256.77 K | $513.54 K | 305.20% | 0.39% |
| TWO SIGMA ADVISERS, LP | 11/14/2025 | 234.04 K | $468.08 K | 100.00% | 0.35% |
| AMH EQUITY LTD | 10/29/2025 | 231.67 K | $463.34 K | 100.00% | 0.35% |
| QUADRATURE CAPITAL LTD | 11/13/2025 | 223.47 K | $448.06 K | 100.00% | 0.34% |
| APTUS CAPITAL ADVISORS, LLC | 11/12/2025 | 210.20 K | $420.40 K | 100.00% | 0.32% |
| GUARDIAN WEALTH ADVISORS, LLC / NC | 11/14/2025 | 210.20 K | $420.40 K | 100.00% | 0.32% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 207.00 K | $414.00 K | 945.45% | 0.31% |
| XTX TOPCO LTD | 11/14/2025 | 187.30 K | $374.60 K | 16.36% | 0.28% |
| ROYAL BANK OF CANADA | 11/14/2025 | 143.40 K | $287.00 K | 302.81% | 0.22% |
| HRT FINANCIAL LP | 11/14/2025 | 138.81 K | $277.00 K | 100.00% | 0.21% |
| VALEO FINANCIAL ADVISORS, LLC | 11/03/2025 | 130.70 K | $261.40 K | 0.00% | 0.20% |
| LPL FINANCIAL LLC | 11/12/2025 | 95.30 K | $190.60 K | 762.44% | 0.14% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 81.20 K | $162.40 K | 89.28% | 0.12% |
| GSA CAPITAL PARTNERS LLP | 11/07/2025 | 78.75 K | $157.00 K | 100.00% | 0.12% |
| CASCADES CAPITAL ASSET MANAGEMENT, LLC | 11/14/2025 | 77.34 K | $154.67 K | 15.19% | 0.12% |
| GEODE CAPITAL MANAGEMENT, LLC | 11/12/2025 | 74.02 K | $148.04 K | 312.20% | 0.11% |
| SIMPLEX TRADING, LLC | 11/12/2025 | 66.92 K | $133.00 K | 100.00% | 0.10% |
| CITADEL ADVISORS LLC | 11/14/2025 | 62.60 K | $125.20 K | 317.33% | 0.09% |
| NORTHERN TRUST CORP | 11/14/2025 | 39.26 K | $78.52 K | -25.93% | 0.06% |
| COLONY GROUP, LLC | 11/14/2025 | 36.00 K | $72.00 K | 0.00% | 0.05% |
| FEDERATION DES CAISSES DESJARDINS DU QUEBEC | 11/14/2025 | 29.78 K | $59.56 K | 129.08% | 0.04% |
| RAYMOND JAMES FINANCIAL INC | 11/14/2025 | 26.60 K | $53.20 K | -38.48% | 0.04% |
| SAFEGUARD INVESTMENT ADVISORY GROUP, LLC | 11/13/2025 | 25.04 K | $50.09 K | 0.00% | 0.04% |
| MARINER, LLC | 11/14/2025 | 25.00 K | $50.00 K | 127.27% | 0.04% |
| CREATIVE PLANNING | 11/14/2025 | 23.41 K | $46.82 K | 0.00% | 0.04% |
| STATE STREET CORP | 11/14/2025 | 22.22 K | $44.44 K | 21.78% | 0.03% |
| STEPHENSON & COMPANY, INC. | 10/21/2025 | 20.00 K | $40.00 K | 100.00% | 0.03% |
| NATIONAL BANK OF CANADA /FI/ | 11/14/2025 | 18.70 K | $37.40 K | 0.00% | 0.03% |
| CITADEL ADVISORS LLC | 11/14/2025 | 17.00 K | $34.00 K | -41.18% | 0.03% |
| BAY RIVERS GROUP | 10/08/2025 | 16.69 K | $33.38 K | 16.55% | 0.03% |
| BANK OF AMERICA CORP /DE/ | 11/14/2025 | 16.05 K | $32.10 K | 200,550.00% | 0.02% |
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Milestone Pharmaceuticals Inc. institutional Ownership - FAQ's
During the previous two years, 78 institutional investors and hedge funds held shares of Milestone Pharmaceuticals Inc.. The most heavily invested institutionals were:
ADAGE CAPITAL PARTNERS GP, L.L.C.: 6.98 M
Propel Bio Management, LLC: 5.12 M
ORBIMED ADVISORS LLC: 3.22 M
MORGAN STANLEY: 2.97 M
Simplify Asset Management Inc.: 2.83 M
RTW INVESTMENTS, LP: 2.51 M
51.43% of Milestone Pharmaceuticals Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 41.65 M shares in the last 24 months. This purchase volume represents approximately $109.95 M in transactions.