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| Reporting Date | Major Shareholder Name | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| 05/15/2024 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 5.33 M | $40.82 M | -3.77% | 10.28% |
| 05/14/2024 | PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC | 4.49 M | $34.43 M | 0.00% | 8.67% |
| 05/15/2024 | SOFINNOVA INVESTMENTS, INC. | 4.28 M | $32.79 M | 0.00% | 8.26% |
| 05/15/2024 | ROCK SPRINGS CAPITAL MANAGEMENT LP | 3.68 M | $28.20 M | 0.00% | 7.10% |
| 05/15/2024 | EVENTIDE ASSET MANAGEMENT, LLC | 3.18 M | $24.36 M | 0.00% | 6.13% |
| 05/10/2024 | BLACKROCK INC. | 3.09 M | $23.66 M | 1.52% | 5.96% |
| 05/15/2024 | SAMLYN CAPITAL, LLC | 2.91 M | $22.31 M | -13.63% | 5.62% |
| 05/14/2024 | AFFINITY ASSET ADVISORS, LLC | 2.64 M | $20.24 M | 40.13% | 5.10% |
| 05/15/2024 | NEA MANAGEMENT COMPANY, LLC | 2.44 M | $18.67 M | 0.00% | 4.70% |
| 05/10/2024 | VANGUARD GROUP INC | 2.42 M | $18.53 M | 1.43% | 4.67% |
| 05/13/2024 | FMR LLC | 1.97 M | $15.07 M | -13.42% | 3.80% |
| 05/15/2024 | SAMSARA BIOCAPITAL, LLC | 1.56 M | $11.97 M | 0.00% | 3.01% |
| 05/15/2024 | SPHERA FUNDS MANAGEMENT LTD. | 1.37 M | $10.52 M | -12.16% | 2.65% |
| 05/15/2024 | BLUE OWL CAPITAL HOLDINGS LP | 1.27 M | $9.73 M | 0.00% | 2.45% |
| 05/13/2024 | GEODE CAPITAL MANAGEMENT, LLC | 1.07 M | $8.18 M | 3.37% | 2.06% |
| 05/15/2024 | WOODLINE PARTNERS LP | 888,067 | $6.80 M | 196.02% | 1.71% |
| 05/15/2024 | STATE STREET CORP | 880,639 | $6.75 M | 17.96% | 1.70% |
| 05/15/2024 | MILLENNIUM MANAGEMENT LLC | 703,606 | $5.39 M | -22.80% | 1.36% |
| 05/14/2024 | KNOTT DAVID M JR | 564,549 | $4.32 M | 0.00% | 1.09% |
| 05/15/2024 | KENNEDY CAPITAL MANAGEMENT LLC | 437,657 | $3.35 M | 52.21% | 0.84% |
| 05/14/2024 | NORTHERN TRUST CORP | 419,879 | $3.22 M | -1.14% | 0.81% |
| 05/15/2024 | GOLDMAN SACHS GROUP INC | 409,923 | $3.14 M | 12.81% | 0.79% |
| 05/15/2024 | LAURION CAPITAL MANAGEMENT LP | 402,197 | $3.08 M | -27.83% | 0.78% |
| 05/15/2024 | EXOME ASSET MANAGEMENT LLC | 273,413 | $2.09 M | 100.00% | 0.53% |
| 05/15/2024 | WELLINGTON MANAGEMENT GROUP LLP | 244,200 | $1.87 M | 100.00% | 0.47% |
| 05/15/2024 | PARKMAN HEALTHCARE PARTNERS LLC | 222,943 | $1.71 M | 4.95% | 0.43% |
| 04/16/2024 | OVERBROOK MANAGEMENT CORP | 219,326 | $1.68 M | 0.00% | 0.42% |
| 05/15/2024 | UBS OCONNOR LLC | 183,218 | $1.40 M | -25.20% | 0.35% |
| 05/10/2024 | DIMENSIONAL FUND ADVISORS LP | 174,647 | $1.34 M | 174.24% | 0.34% |
| 05/13/2024 | RENAISSANCE TECHNOLOGIES LLC | 173,700 | $1.33 M | -20.50% | 0.34% |
| 04/25/2024 | BANK OF NEW YORK MELLON CORP | 164,432 | $1.26 M | 4.06% | 0.32% |
| 05/13/2024 | NUVEEN ASSET MANAGEMENT, LLC | 160,879 | $1.23 M | 0.00% | 0.31% |
| 05/03/2024 | GSA CAPITAL PARTNERS LLP | 131,098 | $1.00 M | -21.50% | 0.25% |
| 05/09/2024 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 126,535 | $969,258 | 4.02% | 0.24% |
| 05/15/2024 | MORGAN STANLEY | 124,246 | $951,724 | 7.59% | 0.24% |
| 05/15/2024 | SUPERSTRING CAPITAL MANAGEMENT LP | 112,739 | $863,581 | -9.04% | 0.22% |
| 05/15/2024 | CITADEL ADVISORS LLC | 92,718 | $710,220 | -41.86% | 0.18% |
| 05/15/2024 | SCHONFELD STRATEGIC ADVISORS LLC | 74,800 | $572,968 | -31.19% | 0.14% |
| 05/09/2024 | RHUMBLINE ADVISERS | 63,137 | $483,619 | 4.72% | 0.12% |
| 05/15/2024 | PRELUDE CAPITAL MANAGEMENT, LLC | 62,445 | $478,329 | 100.00% | 0.12% |
| 05/10/2024 | JPMORGAN CHASE & CO | 61,577 | $471,680 | 79.34% | 0.12% |
| 05/15/2024 | BANK OF AMERICA CORP /DE/ | 59,894 | $458,788 | -18.73% | 0.12% |
| 05/14/2024 | AMERICAN CENTURY COMPANIES INC | 51,427 | $393,931 | 79.22% | 0.10% |
| 05/13/2024 | UBS GROUP AG | 47,960 | $367,374 | 3.79% | 0.09% |
| 05/14/2024 | ALPS ADVISORS INC | 43,560 | $333,670 | 3.19% | 0.08% |
| 05/15/2024 | TWO SIGMA ADVISERS, LP | 41,300 | $316,358 | -41.58% | 0.08% |
| 05/15/2024 | BARCLAYS PLC | 36,909 | $282,000 | -46.60% | 0.07% |
| 05/09/2024 | CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. | 34,832 | $266,813 | 100.00% | 0.07% |
| 05/13/2024 | BALYASNY ASSET MANAGEMENT L.P. | 31,380 | $240,371 | 100.00% | 0.06% |
| 05/07/2024 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 30,154 | $230,980 | -30.93% | 0.06% |
A. During the previous two years, 109 institutional investors and hedge funds held shares of Inozyme Pharma, Inc.. The most heavily invested institutionals were:
ADAGE CAPITAL PARTNERS GP, L.L.C.: 5.33 M
Pivotal bioVenture Partners Investment Advisor LLC: 4.49 M
Sofinnova Investments, Inc.: 4.28 M
Rock Springs Capital Management LP: 3.68 M
EVENTIDE ASSET MANAGEMENT, LLC: 3.18 M
BlackRock Inc.: 3.09 M
A. 96.21% of Inozyme Pharma, Inc. stock is owned by institutional investors.
A. Institutional investors have bought a total of 57.30 M shares in the last 24 months. This purchase volume represents approximately $257.28 M in transactions.
