Septerna, Inc. Major Shareholders & Ownership History
| Major Shareholder Name | Reporting Date | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 11/14/2025 | 7.00 M | $131.59 M | 0.00% | 15.84% |
| TRV GP V, LLC | 11/13/2025 | 6.22 M | $116.92 M | 0.00% | 14.07% |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 11/14/2025 | 4.92 M | $92.54 M | 5.12% | 11.14% |
| TRV GP VI, LLC | 11/13/2025 | 4.21 M | $79.22 M | 0.00% | 9.54% |
| BVF INC/IL | 11/14/2025 | 4.02 M | $75.54 M | -8.65% | 9.09% |
| SAMSARA BIOCAPITAL, LLC | 11/14/2025 | 3.15 M | $59.24 M | 0.00% | 7.13% |
| SIREN, L.L.C. | 11/13/2025 | 2.20 M | $41.43 M | 0.00% | 4.99% |
| VANGUARD GROUP INC | 11/07/2025 | 1.52 M | $28.57 M | 7.38% | 3.44% |
| BLACKROCK, INC. | 11/12/2025 | 1.46 M | $27.46 M | 4.96% | 3.31% |
| GOLDMAN SACHS GROUP INC | 11/14/2025 | 1.45 M | $27.36 M | 2.71% | 3.29% |
| AVORO CAPITAL ADVISORS LLC | 11/14/2025 | 1.34 M | $25.16 M | 8.08% | 3.03% |
| ADAR1 CAPITAL MANAGEMENT, LLC | 11/14/2025 | 1.18 M | $22.13 M | 38.86% | 2.66% |
| VR ADVISER, LLC | 11/14/2025 | 610.81 K | $11.49 M | 13.02% | 1.38% |
| CASDIN CAPITAL, LLC | 11/14/2025 | 553.27 K | $10.41 M | 0.00% | 1.25% |
| GEODE CAPITAL MANAGEMENT, LLC | 11/12/2025 | 545.70 K | $10.27 M | 11.83% | 1.24% |
| PERCEPTIVE ADVISORS LLC | 11/14/2025 | 541.45 K | $10.18 M | 0.00% | 1.23% |
| STATE STREET CORP | 11/14/2025 | 418.96 K | $7.88 M | 13.23% | 0.95% |
| MILLENNIUM MANAGEMENT LLC | 11/14/2025 | 384.20 K | $7.23 M | 639.64% | 0.87% |
| JANE STREET GROUP, LLC | 11/14/2025 | 352.40 K | $6.63 M | -21.39% | 0.80% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 318.80 K | $6.00 M | -39.63% | 0.72% |
| CATALIO CAPITAL MANAGEMENT, LP | 11/14/2025 | 294.36 K | $5.54 M | 0.00% | 0.67% |
| CHECKPOINT CAPITAL L.P. | 11/14/2025 | 283.16 K | $5.33 M | -51.72% | 0.64% |
| WOODLINE PARTNERS LP | 11/14/2025 | 282.59 K | $5.32 M | 0.00% | 0.64% |
| UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH | 10/30/2025 | 222.70 K | $4.19 M | 0.00% | 0.50% |
| SIO CAPITAL MANAGEMENT, LLC | 11/13/2025 | 189.20 K | $3.56 M | -67.63% | 0.43% |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 11/10/2025 | 186.90 K | $3.52 M | 20.75% | 0.42% |
| INVESCO LTD. | 11/13/2025 | 177.07 K | $3.33 M | 1,396.41% | 0.40% |
| NORTHERN TRUST CORP | 11/14/2025 | 167.35 K | $3.15 M | 8.42% | 0.38% |
| TWO SIGMA INVESTMENTS, LP | 11/14/2025 | 92.33 K | $1.74 M | 18.92% | 0.21% |
| RANGELEY CAPITAL, LLC | 11/14/2025 | 88.00 K | $1.66 M | 50.16% | 0.20% |
| LOGOS GLOBAL MANAGEMENT LP | 11/14/2025 | 83.55 K | $1.57 M | -23.49% | 0.19% |
| WALLEYE CAPITAL LLC | 11/14/2025 | 80.34 K | $1.51 M | 100.00% | 0.18% |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 11/14/2025 | 72.60 K | $1.37 M | 163.04% | 0.16% |
| UBS GROUP AG | 11/13/2025 | 59.05 K | $1.11 M | -18.37% | 0.13% |
| LONGAEVA PARTNERS L.P. | 11/14/2025 | 57.06 K | $1.07 M | 100.00% | 0.13% |
| MORGAN STANLEY | 11/14/2025 | 54.46 K | $1.02 M | -35.83% | 0.12% |
| BANK OF NEW YORK MELLON CORP | 11/03/2025 | 51.63 K | $971.18 K | 6.48% | 0.12% |
| BANK OF AMERICA CORP /DE/ | 11/14/2025 | 51.50 K | $968.62 K | -48.10% | 0.12% |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 11/17/2025 | 35.78 K | $672.98 K | 100.00% | 0.08% |
| ALYESKA INVESTMENT GROUP, L.P. | 11/17/2025 | 35.00 K | $658.35 K | 0.00% | 0.08% |
| BARCLAYS PLC | 11/12/2025 | 30.10 K | $566.22 K | -15.69% | 0.07% |
| RHUMBLINE ADVISERS | 11/06/2025 | 27.60 K | $519.22 K | -3.39% | 0.06% |
| PRICE T ROWE ASSOCIATES INC /MD/ | 11/14/2025 | 27.42 K | $516.00 K | 10.13% | 0.06% |
| AMERICAN CENTURY COMPANIES INC | 11/12/2025 | 25.28 K | $475.57 K | 100.00% | 0.06% |
| NUVEEN, LLC | 11/12/2025 | 23.96 K | $450.71 K | -58.67% | 0.05% |
| ALLIANCEBERNSTEIN L.P. | 11/14/2025 | 22.10 K | $415.70 K | 0.00% | 0.05% |
| TWO SIGMA ADVISERS, LP | 11/14/2025 | 20.70 K | $389.37 K | 100.00% | 0.05% |
| WELLS FARGO & COMPANY/MN | 11/13/2025 | 20.15 K | $378.97 K | 36.90% | 0.05% |
| VERITION FUND MANAGEMENT LLC | 11/14/2025 | 20.13 K | $378.66 K | 100.00% | 0.05% |
| SOLEUS CAPITAL MANAGEMENT, L.P. | 11/14/2025 | 18.26 K | $343.47 K | -75.80% | 0.04% |
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Septerna, Inc. institutional Ownership - FAQ's
During the previous two years, 99 institutional investors and hedge funds held shares of Septerna, Inc.. The most heavily invested institutionals were:
RA CAPITAL MANAGEMENT, L.P.: 7 M
TRV GP V, LLC: 6.22 M
DRIEHAUS CAPITAL MANAGEMENT LLC: 4.92 M
TRV GP VI, LLC: 4.21 M
BVF INC/IL: 4.02 M
Samsara BioCapital, LLC: 3.15 M
100.87% of Septerna, Inc. stock is owned by institutional investors.
Institutional investors have bought a total of 44.58 M shares in the last 24 months. This purchase volume represents approximately $1.13 B in transactions.