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| Reporting Date | Major Shareholder Name | Shares Held | Market Value | Change in Shares | Ownership |
|---|---|---|---|---|---|
| 05/15/2024 | RA CAPITAL MANAGEMENT, L.P. | 12.77 M | $148.61 M | 11.82% | 15.82% |
| 05/15/2024 | JANUS HENDERSON GROUP PLC | 12.60 M | $146.65 M | 41.37% | 15.62% |
| 05/15/2024 | RTW INVESTMENTS, LP | 7.38 M | $85.89 M | 32.26% | 9.14% |
| 05/10/2024 | BLACKROCK INC. | 6.64 M | $77.27 M | 21.70% | 8.23% |
| 05/15/2024 | SUVRETTA CAPITAL MANAGEMENT, LLC | 6.30 M | $73.31 M | 28.83% | 7.80% |
| 05/15/2024 | STATE STREET CORP | 5.54 M | $64.53 M | 2.67% | 6.87% |
| 05/10/2024 | VANGUARD GROUP INC | 4.72 M | $54.98 M | 9.64% | 5.85% |
| 05/15/2024 | BVF INC/IL | 4.05 M | $47.11 M | 0.00% | 5.02% |
| 05/14/2024 | PICTET ASSET MANAGEMENT HOLDING SA | 3.71 M | $43.19 M | -18.59% | 4.60% |
| 05/15/2024 | HOLOCENE ADVISORS, LP | 3.45 M | $40.17 M | -1.14% | 4.28% |
| 05/15/2024 | LAURION CAPITAL MANAGEMENT LP | 2.70 M | $31.42 M | -0.18% | 3.35% |
| 05/15/2024 | REDMILE GROUP, LLC | 2.26 M | $26.36 M | 14.99% | 2.81% |
| 05/10/2024 | WESTFIELD CAPITAL MANAGEMENT CO LP | 2.16 M | $25.19 M | 22.88% | 2.68% |
| 05/13/2024 | GEODE CAPITAL MANAGEMENT, LLC | 1.74 M | $20.27 M | 26.36% | 2.16% |
| 05/15/2024 | CITADEL ADVISORS LLC | 1.57 M | $18.27 M | -27.95% | 1.95% |
| 05/15/2024 | MILLENNIUM MANAGEMENT LLC | 1.09 M | $12.65 M | 94.53% | 1.35% |
| 05/15/2024 | FRAZIER LIFE SCIENCES MANAGEMENT, L.P. | 1.00 M | $11.64 M | -50.00% | 1.24% |
| 05/15/2024 | BIOIMPACT CAPITAL LLC | 967,742 | $11.26 M | 100.00% | 1.20% |
| 05/15/2024 | SUPERSTRING CAPITAL MANAGEMENT LP | 941,287 | $10.96 M | -7.85% | 1.17% |
| 05/13/2024 | FRANKLIN RESOURCES INC | 827,657 | $9.63 M | -0.01% | 1.03% |
| 05/15/2024 | MORGAN STANLEY | 812,622 | $9.46 M | -45.43% | 1.01% |
| 05/15/2024 | ORCHARD CAPITAL MANAGEMENT, LLC | 749,350 | $8.72 M | 1.37% | 0.93% |
| 05/15/2024 | GOLDMAN SACHS GROUP INC | 744,948 | $8.67 M | 18.04% | 0.92% |
| 05/14/2024 | NORTHERN TRUST CORP | 714,531 | $8.32 M | 15.62% | 0.89% |
| 05/09/2024 | EAGLE ASSET MANAGEMENT INC | 679,767 | $7.29 M | -3.18% | 0.84% |
| 05/09/2024 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 629,233 | $7.32 M | 26.01% | 0.78% |
| 05/13/2024 | NUVEEN ASSET MANAGEMENT, LLC | 550,594 | $6.41 M | 127.15% | 0.68% |
| 05/15/2024 | SPHERA FUNDS MANAGEMENT LTD. | 515,882 | $6.00 M | 26.23% | 0.64% |
| 05/14/2024 | UNIVERSITY OF WISCONSIN FOUNDATION | 498,137 | $5.80 M | 293.73% | 0.62% |
| 05/15/2024 | CAPTION MANAGEMENT, LLC | 474,900 | $5.53 M | 0.00% | 0.59% |
| 05/09/2024 | ABRDN PLC | 470,387 | $5.48 M | 119.61% | 0.58% |
| 05/13/2024 | RAFFERTY ASSET MANAGEMENT, LLC | 461,952 | $5.38 M | 1.82% | 0.57% |
| 05/15/2024 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 450,000 | $5.24 M | -85.60% | 0.56% |
| 05/07/2024 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 446,500 | $5.20 M | -5.92% | 0.55% |
| 05/10/2024 | CITIGROUP INC | 418,259 | $4.87 M | 94.90% | 0.52% |
| 05/15/2024 | BANK OF AMERICA CORP /DE/ | 408,639 | $4.76 M | 50.29% | 0.51% |
| 05/15/2024 | BARCLAYS PLC | 354,088 | $4.12 M | -34.86% | 0.44% |
| 05/13/2024 | UBS GROUP AG | 320,732 | $3.73 M | 12.74% | 0.40% |
| 05/06/2024 | CANDRIAM S.C.A. | 310,000 | $3.61 M | 10.71% | 0.38% |
| 05/15/2024 | WELLINGTON MANAGEMENT GROUP LLP | 307,924 | $3.58 M | 28.82% | 0.38% |
| 05/15/2024 | ALYESKA INVESTMENT GROUP, L.P. | 300,000 | $3.49 M | -48.56% | 0.37% |
| 05/15/2024 | INTEGRAL HEALTH ASSET MANAGEMENT, LLC | 300,000 | $3.49 M | 100.00% | 0.37% |
| 05/15/2024 | NEWTYN MANAGEMENT, LLC | 250,000 | $2.91 M | -8.26% | 0.31% |
| 04/25/2024 | BANK OF NEW YORK MELLON CORP | 248,746 | $2.90 M | 11.84% | 0.31% |
| 05/15/2024 | TWO SIGMA INVESTMENTS, LP | 246,100 | $2.86 M | 91.13% | 0.31% |
| 05/14/2024 | ALLIANCEBERNSTEIN L.P. | 231,007 | $2.69 M | -22.74% | 0.29% |
| 05/07/2024 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 179,962 | $2.09 M | 8.27% | 0.22% |
| 05/15/2024 | PARKMAN HEALTHCARE PARTNERS LLC | 179,899 | $2.09 M | -18.02% | 0.22% |
| 05/07/2024 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 171,100 | $1.99 M | 31.51% | 0.21% |
| 05/16/2024 | COMERICA BANK | 171,000 | $1.99 M | 9.66% | 0.21% |
A. During the previous two years, 192 institutional investors and hedge funds held shares of 89bio, Inc.. The most heavily invested institutionals were:
RA CAPITAL MANAGEMENT, L.P.: 12.77 M
JANUS HENDERSON GROUP PLC: 12.6 M
RTW INVESTMENTS, LP: 7.38 M
BlackRock Inc.: 6.64 M
SUVRETTA CAPITAL MANAGEMENT, LLC: 6.3 M
STATE STREET CORP: 5.54 M
A. 121.08% of 89bio, Inc. stock is owned by institutional investors.
A. Institutional investors have bought a total of 119.80 M shares in the last 24 months. This purchase volume represents approximately $896.07 M in transactions.
